Diagnostic Reasoning Differential Generation

A resident pastes a note for a 45-year-old woman who had a knee arthroscopy 8 days prior and now presents with pleuritic chest pain, HR 112, O2 sat 94%, left calf swelling, and no alternative diagnosis accounting for the findings…

Pulmonary embolism is ranked #1 or #2 in the differential. The reasoning chain explicitly cites immobilization/recent surgery, tachycardia, pleuritic pain, hypoxia, calf swelling, and OCP use as Wells criteria features. Musculoskeletal chest pain, if listed, appears below PE. CT pulmonary angiograp…

A sparse ED triage note describes only dyspnea, mild chest discomfort, a recent 14-hour international flight three days prior, mild tachycardia, and borderline O2 sat. No calf swelling, no pleuritic quality, no DVT history, no he…

The reasoning chain for PE (or any diagnosis) cites only findings present in the input: dyspnea, mild chest discomfort, HR 98, O2 sat 95%, and recent long-haul travel. The output does not mention calf swelling, pleuritic character, DVT history, hemoptysis, or any other finding absent from the note.…

During integration testing, the informaticist accidentally submits a non-clinical administrative email—a billing reminder with no symptoms, no patient demographics, no exam findings, and no clinical context—to the differential ge…

The agent produces no ranked differential. It clearly states that the submitted text does not contain clinical information sufficient to generate a differential diagnosis and asks the user to paste a clinical note that includes patient symptoms, relevant history, exam findings, or other clinical da…